Genetically modified α-amylase inhibitor peas are not specifically allergenic in mice
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چکیده
منابع مشابه
Genetically modified α-amylase inhibitor peas are not specifically allergenic in mice
Weevils can devastate food legumes in developing countries, but genetically modified peas (Pisum sativum), chickpeas and cowpeas expressing the gene for alpha-amylase inhibitor-1 (αAI) from the common bean (Phaseolus vulgaris) are completely protected from weevil destruction. αAI is seed-specific, accumulated at high levels and undergoes post-translational modification as it traverses the seed ...
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The development of modern gene technologies allows for the expression of recombinant proteins in non-native hosts. Diversity in translational and post-translational modification pathways between species could potentially lead to discrete changes in the molecular architecture of the expressed protein and subsequent cellular function and antigenicity. Here, we show that transgenic expression of a...
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ژورنال
عنوان ژورنال: Clinical and Translational Allergy
سال: 2013
ISSN: 2045-7022
DOI: 10.1186/2045-7022-3-s3-p84